Description

4-Bromobenzoic-D4 Acid is a deuterated isotopologue of 4-bromobenzoic acid, where four hydrogen atoms are replaced with deuterium. This compound is a critical building block and internal standard in analytical chemistry, particularly for mass spectrometry and NMR spectroscopy. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, isotopically labeled compounds for quantitative analysis, metabolic studies, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Quantitative Analysis: Used as a stable isotope-labeled internal standard in LC-MS and GC-MS for the accurate quantification of 4-bromobenzoic acid and related metabolites in complex biological and environmental matrices.
• Pharmaceutical Research: Serves as a key intermediate in the synthesis of deuterated drug candidates, leveraging the kinetic isotope effect to potentially improve metabolic stability and pharmacokinetic profiles.
• Metabolic Pathway Tracing: Employed in tracer studies to investigate the metabolic fate and degradation pathways of brominated aromatic compounds.
• NMR Spectroscopy: Acts as a valuable probe in NMR studies due to the distinct spectroscopic properties of deuterium, aiding in structural elucidation and mechanistic investigations.
• Agrochemical Development: Used in the research and development of novel, isotopically labeled pesticides and herbicides for environmental and residue studies.
• Material Science: A potential precursor for synthesizing deuterated organic semiconductors or liquid crystals, where isotopic substitution can fine-tune electronic and physical properties.

Basic Information

Product Name	4-Bromobenzoic-D4 Acid
CAS No.	787624-24-2
Molecular Formula	C7D4BrO2
Molecular Weight	189.02 g/mol
Synonyms	4-Bromo-D4-benzoic Acid; Benzoic-2,3,5,6-d4 Acid, 4-Bromo-; p-Bromobenzoic-d4 Acid; Deuteron-p-Bromobenzoic Acid; [2,3,5,6-2H4]-4-Bromobenzoic Acid; 4-Bromobenzoic Acid-d4; (2,3,5,6-2H4)4-Bromobenzoic Acid
EINECS	Contact for details

Quality Control

Our 4-Bromobenzoic-D4 Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C) for structural confirmation and deuterium incorporation, HPLC for chemical purity, and mass spectrometry to verify isotopic enrichment. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Deuterium Enrichment (NMR/MS)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.