Description

1H-Inden-1-One,3-Amino-2,3-Dihydro-2-Hydroxy-5-Methoxy-,cis-(9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its specific cis-configuration and functionalized indanone scaffold. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry and drug discovery programs. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to develop novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds and natural product analogs due to its reactive amino and hydroxy groups.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialty chemicals, dyes, and advanced materials requiring a specific stereochemical configuration.
• Academic & Industrial R&D: Utilized in chemical research for developing novel synthetic methodologies and exploring new chemical spaces.

Basic Information

Item	Details
Product Name	1H-Inden-1-One,3-Amino-2,3-Dihydro-2-Hydroxy-5-Methoxy-,cis-(9Ci)
CAS No.	785749-29-3
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	cis-3-Amino-2,3-dihydro-2-hydroxy-5-methoxy-1H-inden-1-one; (1R,2S)-3-Amino-2-hydroxy-5-methoxy-2,3-dihydro-1H-inden-1-one; 5-Methoxy-3-amino-2-hydroxyindan-1-one (cis); 3-Amino-2-hydroxy-5-methoxyindan-1-one; cis-3-Amino-2-hydroxy-5-methoxyindan-1-one; 1H-Inden-1-one, 3-amino-2,3-dihydro-2-hydroxy-5-methoxy-, (1R,2S)-; (1R,2S)-3-Amino-2-hydroxy-5-methoxyindan-1-one
EINECS	Contact for details

Quality Control

Our 1H-Inden-1-One,3-Amino-2,3-Dihydro-2-Hydroxy-5-Methoxy-,cis-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be stored away from light. It may also be hygroscopic; therefore, containers must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.