Description

Ethyl 3-Bromobenzo[B]Thiophene-2-Carboxylate is a high-value brominated heterocyclic building block, specifically an ester derivative of benzothiophene. This compound is essential for advanced organic synthesis, offering a versatile reactive site for cross-coupling reactions and further functionalization. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the research and development of organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Biology: Employed as a molecular probe or tag in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in synthetic organic chemistry.

Basic Information

Product Name	Ethyl 3-Bromobenzo[B]Thiophene-2-Carboxylate
CAS No.	784163-17-3
Molecular Formula	C11H9BrO2S
Molecular Weight	285.16 g/mol
Synonyms	Ethyl 3-Bromobenzo[B]Thiophene-2-Carboxylate; 3-Bromobenzo[B]thiophene-2-carboxylic Acid Ethyl Ester; Ethyl 3-Bromobenzo[B]thiophene-2-Carboxylate; 2-Carbethoxy-3-bromobenzo[B]thiophene; 3-Bromo-2-ethoxycarbonylbenzo[B]thiophene; Benzo[B]thiophene-2-carboxylic acid, 3-bromo-, ethyl ester; Ethyl 3-bromobenzo[B]thienyl-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromobenzo[B]Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.