Description

L-Proline, 4-Mercapto-1-Methyl-, (4S)- (9Ci) is a high-purity, non-proteinogenic amino acid derivative featuring a unique thiol-functionalized proline scaffold. This compound matters as a versatile chiral building block and ligand, enabling the synthesis of complex molecules and facilitating advanced research in asymmetric catalysis. It is primarily needed by pharmaceutical researchers for developing novel therapeutics and by specialty chemical manufacturers producing fine chemicals and catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of protease inhibitors, enzyme modulators, and other bioactive molecules.
• Catalyst Ligand: Used in the design and synthesis of novel organocatalysts and metal-complexing ligands for asymmetric synthesis.
• Peptide Chemistry: Serves as a modified amino acid residue for constructing structurally unique peptides with enhanced stability or novel functionality.
• Biochemical Research: Employed as a tool compound in enzymatic studies and for probing protein structure-function relationships.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex natural products and specialty organic compounds.

Basic Information

Product Name	L-Proline, 4-Mercapto-1-Methyl-, (4S)- (9Ci)
CAS No.	784132-86-1
Molecular Formula	C6H11NO2S
Molecular Weight	161.22 g/mol
Synonyms	(4S)-4-Mercapto-1-methyl-L-proline; 1-Methyl-4-mercapto-L-proline; (2S,4S)-1-Methyl-4-mercaptopyrrolidine-2-carboxylic acid; 4-Thia-L-proline, 1-methyl- derivative; 4-Mercapto-1-methylproline; L-1-Methyl-4-mercaptoproline; Modified L-Proline derivative; Thiol-functionalized proline
EINECS	Contact for details

Quality Control

Our L-Proline, 4-Mercapto-1-Methyl-, (4S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation. Keep the container tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.