Description

2-Thiophenecarboxylicacid,3-Aminotetrahydro-,trans-(9Ci) is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a carboxylic acid group with a chiral, saturated aminothiophene moiety, which is critical for constructing complex molecules with specific stereochemistry and functionality. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, drug discovery, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system or infectious diseases.
• Medicinal Chemistry Building Block: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities and optimize drug candidate properties.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and herbicides, leveraging its heterocyclic core.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis or metal-organic frameworks (MOFs) due to its chelating potential.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fine chemicals and specialty materials requiring precise stereochemical control.

Basic Information

Product Name	2-Thiophenecarboxylicacid,3-Aminotetrahydro-,trans-(9Ci)
CAS No.	783276-61-9
Molecular Formula	C6H9NO2S
Molecular Weight	159.21 g/mol
Synonyms	trans-3-Aminotetrahydro-2-thiophenecarboxylic acid; (2R,3S)-3-Amino-3,4-dihydro-2H-thiophene-2-carboxylic acid; 3-Amino-4,5-dihydrothiophene-2-carboxylic acid, trans-; 3-Aminotetrahydrothiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 3-aminohexahydro-, trans-; 783276-61-9; (2R,3S)-3-Aminotetrahydrothiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylicacid,3-Aminotetrahydro-,trans-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including chiral HPLC and NMR, to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.