Description

2-Ethoxy-3-Trimethylsilanyl-Pyridine is a specialized organosilicon-protected pyridine derivative, a key building block in advanced organic synthesis. Its value lies in its dual functionality, where the ethoxy and trimethylsilyl groups act as protective and directing moieties, enabling precise and efficient chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and complex intermediates where selective reactivity is paramount.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in heterocyclic chemistry.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides requiring specific pyridine-based scaffolds.
• Ligand Precursor: Serves as a starting material for the development of specialized ligands in catalysis and material science.
• Functional Material Research: Employed in the creation of organic electronic materials and advanced polymers.
• Cross-Coupling Reactions: Acts as a substrate or intermediate in palladium-catalyzed and other metal-mediated coupling reactions.
• Protecting Group Chemistry: The trimethylsilyl group can be used for the temporary protection of sensitive functional groups during multi-step syntheses.

Basic Information

Product Name	2-Ethoxy-3-Trimethylsilanyl-Pyridine
CAS No.	782479-88-3
Molecular Formula	C10H17NOSi
Molecular Weight	195.34 g/mol
Synonyms	3-((Trimethylsilyl)oxy)-2-ethoxypyridine; 2-Ethoxy-3-(trimethylsilyl)pyridine; 2-Ethoxy-3-(trimethylsiloxy)pyridine; Pyridine, 2-ethoxy-3-(trimethylsilyl)-; 2-Ethoxy-3-trimethylsilylpyridine; 2-Ethoxy-3-TMS-pyridine
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-3-Trimethylsilanyl-Pyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications. Our commitment to quality assurance supports compliance with cGMP and ISO standards for reliable integration into your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.