Description

Bicyclo[2.2.1]Heptane-2-Acetic Acid, 5-Methylene-, Ethyl Ester, (1R,2S,4R)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic compound that serves as a critical chiral building block and advanced intermediate in sophisticated organic syntheses. Its unique, rigid molecular framework and defined stereochemistry make it invaluable for constructing complex target molecules with precise three-dimensional architecture. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-fidelity intermediates for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its bicyclic structure contributes to biological activity and environmental stability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Advanced Material Monomer: Employed in polymer chemistry to introduce rigid, aliphatic segments into specialty polymers, influencing thermal and mechanical properties.
• Fragrance & Flavor Chemistry: Acts as a precursor for synthetic musk compounds and other complex odorants due to its stable, polycyclic nature.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including cycloaddition reactions and stereochemistry research.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptane-2-Acetic Acid, 5-Methylene-, Ethyl Ester, (1R,2S,4R)-Rel- (9Ci)
CAS No.	780789-83-5
Molecular Formula	C12H18O2
Molecular Weight	194.27 g/mol
Synonyms	rel-(1R,2S,4R)-5-Methylenebicyclo[2.2.1]heptane-2-acetic acid ethyl ester; Ethyl 5-methylenebicyclo[2.2.1]heptane-2-acetate; 5-Methylenenorbornane-2-acetic acid ethyl ester; Bicyclo[2.2.1]heptane-2-acetic acid, 5-methylene-, ethyl ester, (1R,2S,4R)-rel-; Ethyl (rel-(1R,2S,4R)-5-methylenebicyclo[2.2.1]heptan-2-yl)acetate
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Acetic Acid, 5-Methylene-, Ethyl Ester, (1R,2S,4R)-Rel- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including chiral purity assessment by HPLC, to confirm identity and meet rigorous specifications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.