Description

Isoquinoline, 7-Bromo-1,2,3,4-Tetrahydro-6-Methyl- (9Ci) is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for the synthesis of complex molecules, offering a unique brominated tetrahydroisoquinoline scaffold for structure-activity relationship (SAR) studies and lead optimization. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to develop new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, anti-cancer agents, and antimicrobials.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides with new modes of action.
• Organic Synthesis & Catalysis: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in catalytic systems due to the reactive bromine substituent.
• Material Science: Investigated for the development of organic semiconductors, liquid crystals, and photoactive materials.
• Academic & Contract Research: Essential for medicinal chemistry programs, library synthesis, and methodological studies in university and CRO laboratories.

Basic Information

Product Name	Isoquinoline, 7-Bromo-1,2,3,4-Tetrahydro-6-Methyl- (9Ci)
CAS No.	780738-23-0
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	7-Bromo-6-methyl-1,2,3,4-tetrahydroisoquinoline; 6-Methyl-7-bromo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-7-bromo-6-methylisoquinoline; 7-Bromo-6-methyl-3,4-dihydro-1H-isoquinoline; 7-Bromo-6-methyl-1,2,3,4-tetrahydroisoquinoline (9CI); 780738-23-0; SCHEMBL21804027; AKOS040759957; ZINC000095839664
EINECS	Contact for details

Quality Control

Our Isoquinoline, 7-Bromo-1,2,3,4-Tetrahydro-6-Methyl- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and regulatory support, meeting the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.