Description

D-Glucopyranosiduronic Acid, Methyl 1-Thio- (9Ci) is a specialized thioglycoside derivative of glucuronic acid, serving as a crucial synthetic intermediate and biochemical probe. Its value lies in its unique structure, which combines a thio-glycosidic bond with a carboxylic acid functionality, enabling precise chemical modifications and biological studies. This compound is essential for researchers and manufacturers in pharmaceutical development, carbohydrate chemistry, and glycobiology, where it is used to create novel drug candidates, enzyme inhibitors, and complex oligosaccharides.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of glycosidase inhibitors, prodrugs, and targeted therapeutics.
• Glycobiology Research: Used as a substrate or inhibitor in enzymatic studies to understand glycosyltransferase and glycosidase mechanisms.
• Carbohydrate Chemistry: Serves as a versatile starting material for the preparation of complex oligosaccharides and glycoconjugates via selective functionalization.
• Bioconjugation & Probe Development: The thioether linkage and carboxylic acid group facilitate site-specific labeling and conjugation to biomolecules for diagnostic and imaging applications.
• Material Science: Potential use in creating functionalized polymers and hydrogels with bioactive sugar moieties.

Basic Information

Product Name	D-Glucopyranosiduronic Acid, Methyl 1-Thio- (9Ci)
CAS No.	780711-63-9
Molecular Formula	C7H12O7S
Molecular Weight	240.23 g/mol
Synonyms	Methyl 1-Thio-β-D-glucopyranosiduronic Acid; Methyl 1-Thio-β-D-glucuronide; 1-Thio-β-D-glucopyranosiduronic Acid Methyl Ester; Methyl β-D-Thioglucuronide; Thiomethyl β-D-glucuronide; β-D-Glucopyranosiduronic acid, methyl 1-thio-; Methyl 1-S-β-D-glucopyranosiduronate
EINECS	Contact for details

Quality Control

Our D-Glucopyranosiduronic Acid, Methyl 1-Thio- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.