Description

Isoquinoline, 5-(3-Azetidinyloxy)- (9Ci) is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines isoquinoline and azetidine pharmacophores. This compound is of significant interest for its potential role in the discovery and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities (NCEs).

Application

• Medicinal Chemistry & Drug Discovery: Serves as a key building block for synthesizing novel small molecule libraries targeting various disease pathways.
• Pharmaceutical Intermediate: Used in the research-scale synthesis of potential active pharmaceutical ingredients (APIs), especially for CNS disorders.
• Biochemical Research: Employed as a reference standard or probe compound in pharmacological and receptor binding studies.
• Process Chemistry Development: Acts as a critical intermediate for optimizing synthetic routes and scaling up candidate molecules.
• Academic Research: Utilized in universities and institutes for studying heterocyclic chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	Isoquinoline, 5-(3-Azetidinyloxy)- (9Ci)
CAS No.	780021-95-6
Molecular Formula	C12H12N2O
Molecular Weight	200.24 g/mol
Synonyms	5-(Azetidin-3-yloxy)isoquinoline; 3-(Isoquinolin-5-yloxy)azetidine; Azetidine, 3-(5-isoquinolinyloxy)-; 5-(3-Azetidinyloxy)isoquinoline; 780021-95-6; AI3-63185; SCHEMBL2184241; ZINC000004143756
EINECS	Contact for details

Quality Control

Our Isoquinoline, 5-(3-Azetidinyloxy)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.