Description

1-Azabicyclo[2.2.2]Octan-3-Amine,2-Methyl-,(2R,3S)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic amine building block of significant interest in advanced organic synthesis. This compound matters as a critical chiral intermediate for constructing complex molecular architectures with precise three-dimensional control, enabling the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, asymmetric catalysis, and the synthesis of natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize sophisticated ligands for transition metal catalysis, enabling highly enantioselective transformations.
• Medicinal Chemistry Scaffold: Serves as a rigid, three-dimensional core structure for constructing focused libraries in structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Employed in the development of novel, chiral pesticides and herbicides where specific stereochemistry is crucial for bioactivity.
• Academic & Industrial Research: A valuable tool for methodological development in organic synthesis and for exploring new chemical space in material science.

Basic Information

Item	Details
Product Name	1-Azabicyclo[2.2.2]Octan-3-Amine,2-Methyl-,(2R,3S)-Rel-(9Ci)
CAS No.	779319-69-6
Molecular Formula	C8H16N2
Molecular Weight	140.23 g/mol
Synonyms	(2R,3S)-2-Methyl-3-aminoquinuclidine; rel-(2R,3S)-2-Methyl-3-aminoquinuclidine; 2-Methyl-3-aminoquinuclidine (relative stereochemistry); 3-Amino-2-methylquinuclidine; 1-Azabicyclo[2.2.2]octan-3-amine, 2-methyl-, (2R,3S)-rel-; Quinuclidin-3-amine, 2-methyl-, (2R,3S)-rel-; Bicyclic amine intermediate 779319-69-6
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.2]Octan-3-Amine,2-Methyl-,(2R,3S)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.