Description

Cyclopenta[B]Pyrrole-2-Carboxylic Acid, Octahydro-, Methyl Ester, (2Alpha,3Abeta,6Abeta)- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex, stereochemically defined bicyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder therapeutics. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop new drug candidates with high stereochemical fidelity and purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug molecules targeting complex biological pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural unit in the multi-step synthesis of proprietary APIs, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Asymmetric Synthesis: Utilized in chiral pool synthesis due to its defined stereocenters, enabling the construction of complex, enantiomerically pure molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Cyclopenta[B]Pyrrole-2-Carboxylic Acid, Octahydro-, Methyl Ester, (2Alpha,3Abeta,6Abeta)- (9Ci)
CAS No.	779293-26-4
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	(2α,3aβ,6aβ)-Octahydrocyclopenta[b]pyrrole-2-carboxylic acid methyl ester; Methyl (2α,3aβ,6aβ)-octahydro-1H-cyclopenta[b]pyrrole-2-carboxylate; (2Alpha,3Abeta,6Abeta)-Octahydrocyclopenta[b]pyrrole-2-carboxylic Acid Methyl Ester; 779293-26-4; Cyclopentapyrrole carboxylate methyl ester derivative; Octahydro-1H-cyclopenta[b]pyrrole-2-carboxylic acid, methyl ester, (2α,3aβ,6aβ)-
EINECS	Contact for details

Quality Control

Our Cyclopenta[B]Pyrrole-2-Carboxylic Acid, Octahydro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided for every shipment, and we can support development under ICH Q7 guidelines and cGMP standards for advanced projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.