Description

1,2,4-Triazolo[3,4-A]Isoquinoline-5-Thiol is a specialized heterocyclic organic compound featuring a fused triazolo-isoquinoline core with a thiol functional group. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a core structure for developing new pesticides, herbicides, and fungicides with potential novel modes of action.
• Organic Synthesis Building Block: Utilized in constructing complex heterocyclic systems for material science and chemical research due to its reactive thiol and fused ring system.
• Ligand in Coordination Chemistry: The thiol and nitrogen atoms can act as donor sites for metal coordination, useful in catalysis and material design.
• Fluorescent Probe Development: The conjugated isoquinoline-triazole structure has potential applications in the design of fluorescent dyes and sensors.

Basic Information

Product Name	1,2,4-Triazolo[3,4-A]Isoquinoline-5-Thiol
CAS No.	779268-51-8
Molecular Formula	C10H6N4S
Molecular Weight	214.25 g/mol
Synonyms	5-Mercapto-[1,2,4]triazolo[3,4-a]isoquinoline; [1,2,4]Triazolo[3,4-a]isoquinoline-5-thiol; 1,2,4-Triazolo[3,4-a]isoquinoline-5-thiol; 5H-[1,2,4]Triazolo[3,4-a]isoquinoline-5-thione; Isoquinoline-5-thiol, 1,2,4-triazolo[3,4-a]-; 779268-51-8; 1,2,4-Triazolo(3,4-a)isoquinoline-5-thiol
EINECS	Contact for details

Quality Control

Our production of 1,2,4-Triazolo[3,4-A]Isoquinoline-5-Thiol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.