Description

(2-Oxo-2-Thiophen-2-Yl-Ethyl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiophene-based structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel therapeutic agents, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the development of new drug candidates, particularly in areas requiring heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new molecules with thiophene moieties.
• API Synthesis: Serves as a precursor in the production of complex Active Pharmaceutical Ingredients (APIs) requiring specific heterocyclic frameworks.
• Chemical Biology Probes: Employed in the development of specialized probes and tools for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Item	Detail
Product Name	(2-Oxo-2-Thiophen-2-Yl-Ethyl)-Carbamic Acid tert-Butyl Ester
CAS No.	778617-77-9
Molecular Formula	C11H15NO3S
Molecular Weight	241.31 g/mol
Synonyms	tert-Butyl N-(2-oxo-2-thiophen-2-ylethyl)carbamate; N-(2-Oxo-2-(thiophen-2-yl)ethyl)carbamic Acid tert-Butyl Ester; 2-[(tert-Butoxycarbonyl)amino]-1-(thiophen-2-yl)ethan-1-one; Boc-2-amino-1-(2-thienyl)ethanone; (Boc-amino)(2-thienyl)methanone; 778617-77-9; tert-Butyl (2-oxo-2-(thiophen-2-yl)ethyl)carbamate
EINECS	Contact for details

Quality Control

Our (2-Oxo-2-Thiophen-2-Yl-Ethyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.