Description

Benzenethiol, 2-(Aminomethyl)-3-Fluoro- (9Ci) is a specialized fluorinated aromatic building block that combines a thiol group with an aminomethyl substituent. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for creating novel active ingredients, particularly in medicinal chemistry programs targeting sulfur- and fluorine-containing compounds. The CAS number for this compound is 777825-22-6.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in areas requiring fluorinated thiophenol motifs.
• Agrochemical Research: Used in developing new pesticides and herbicides where the fluorine atom and thiol group can enhance biological activity and stability.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science.
• Peptide Mimetics & Conjugation: The reactive thiol and amine groups allow for site-specific bioconjugation and the construction of peptide-like structures.
• Polymer Modification: Can be incorporated into polymer chains to introduce specific functional groups, altering material properties.
• Chemical Biology Probes: Useful for developing probes and tools to study biological systems due to its dual functionality.

Basic Information

Item	Details
Product Name	Benzenethiol, 2-(Aminomethyl)-3-Fluoro- (9Ci)
CAS No.	777825-22-6
Molecular Formula	C7H8FNS
Molecular Weight	157.21 g/mol
Synonyms	2-(Aminomethyl)-3-fluorobenzenethiol; 3-Fluoro-2-(aminomethyl)benzenethiol; 2-(Aminomethyl)-3-fluorothiophenol; (3-Fluoro-2-mercaptophenyl)methanamine; 777825-22-6; AI3-40425; SCHEMBL21842227; DTXSID90664669
EINECS	Contact for details

Quality Control

Every batch of Benzenethiol, 2-(Aminomethyl)-3-Fluoro- (9Ci) is produced and analyzed under strict quality management protocols. We ensure high purity and consistency suitable for demanding research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee reliable and reproducible performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. This compound is easily oxidized; prolonged exposure to air should be avoided. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.