Description

Bicyclo[2.2.2]Oct-5-Ene-2-Carboxylic Acid, (1R,2S,4R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid bicyclic framework and defined stereochemistry make it a valuable precursor for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric catalysis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Catalysis Ligand Precursor: Used to synthesize novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Synthesis: Employed in the development of advanced, stereospecific pesticides and herbicides where the defined spatial orientation is critical for bioactivity.
• Material Science Research: Acts as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties derived from its strained bicyclic structure.
• Academic & Industrial R&D: A versatile tool for methodological studies in organic chemistry, including Diels-Alder reactions and other cycloadditions.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	Bicyclo[2.2.2]Oct-5-Ene-2-Carboxylic Acid, (1R,2S,4R)- (9Ci)
CAS No.	777088-05-8
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	(1R,2S,4R)-Bicyclo[2.2.2]oct-5-ene-2-carboxylic acid; (1R,2S,4R)-Bicyclo[2.2.2]oct-5-ene-2-carboxylic Acid; endo-Bicyclo[2.2.2]oct-5-ene-2-carboxylic acid, (1R,2S,4R)-; (1R,2S,4R)-rel-Bicyclo[2.2.2]oct-5-ene-2-carboxylic Acid; Bicyclo[2.2.2]oct-5-ene-2-carboxylic acid, (1R,2S,4R)-rel-; (1R,2S,4R)-Bicyclo[2.2.2]oct-5-ene-2-carboxylic Acid (9CI)
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Oct-5-Ene-2-Carboxylic Acid, (1R,2S,4R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.