Description

2-(3-Hydroxymethylphenyl)Thiophene-3-Carboxylic Acid is a high-purity, multifunctional organic building block of significant interest in advanced chemical synthesis. Its unique molecular architecture, featuring both a carboxylic acid and a hydroxymethyl group on a thiophene-phenyl core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and industrial R&D departments engaged in pharmaceutical development, materials science, and specialty chemical manufacturing, where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Ligand and Catalyst Development: Used to create sophisticated ligands for metal-organic frameworks (MOFs) or catalysts in asymmetric synthesis, leveraging its chelating potential.
• Polymer and Material Science: Serves as a monomer or functionalizing agent for developing specialty polymers, conductive materials, or liquid crystals with tailored electronic and optical properties.
• Agrochemical Research: Employed in the design and synthesis of new-generation herbicides or fungicides with improved efficacy and environmental profiles.
• Organic Electronic Materials: A building block for synthesizing advanced organic semiconductors used in OLEDs, organic photovoltaics (OPVs), or field-effect transistors (OFETs).
• Chemical Biology Probes: Utilized to develop fluorescent tags or molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	2-(3-Hydroxymethylphenyl)Thiophene-3-Carboxylic Acid
CAS No.	776312-23-3
Molecular Formula	C12H10O3S
Molecular Weight	234.27 g/mol
Synonyms	3-Thiophenecarboxylic acid, 2-[3-(hydroxymethyl)phenyl]-; 2-(3-(Hydroxymethyl)phenyl)thiophene-3-carboxylic acid; [3-(3-Carboxythiophen-2-yl)phenyl]methanol; 2-(3-Hydroxymethyl-phenyl)-thiophene-3-carboxylic acid; Thiophene-3-carboxylic acid, 2-(3-hydroxymethylphenyl)-; 776312-23-3
EINECS	Contact for details

Quality Control

Our 2-(3-Hydroxymethylphenyl)Thiophene-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.