Description

2H-Indole-2-Carboxylicacid,3,3A,4,5,6,7-Hexahydro-,(2S-Cis)-(9Ci) is a high-purity, stereochemically defined indole derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique fused bicyclic structure and specific (2S-cis) configuration make it invaluable for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals requiring high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a model substrate in the development of new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Serves as a building block for synthesizing specialty chemicals, flavors, and fragrances requiring complex indole-based structures.
• Academic & Institutional Research: Utilized in university and R&D lab settings for studying heterocyclic chemistry, reaction mechanisms, and natural product synthesis.

Basic Information

Product Name	2H-Indole-2-Carboxylicacid,3,3A,4,5,6,7-Hexahydro-,(2S-Cis)-(9Ci)
CAS No.	775555-78-7
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2S,3aS)-Hexahydro-1H-indole-2-carboxylic acid; (2S-cis)-Octahydroindole-2-carboxylic acid; (2S,3aS)-Octahydroindole-2-carboxylic acid; cis-(2S,3aS)-Octahydroindole-2-carboxylic acid; (2S,3aS)-2-Carboxyhexahydroindole; L-cis-Octahydroindole-2-carboxylic acid; 2H-Indole-2-carboxylic acid, 3,3a,4,5,6,7-hexahydro-, (2S-cis)-; 775555-78-7
EINECS	Contact for details

Quality Control

Every batch of 2H-Indole-2-Carboxylicacid,3,3A,4,5,6,7-Hexahydro-,(2S-Cis)-(9Ci) is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and stereochemical integrity. Our products are suitable for use in GMP-regulated environments, and we provide full traceability. Certificates of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and residual solvent levels are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.