Description

3-Bromo-2-Methylindole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern organic synthesis. This compound serves as a key building block in the development of complex heterocyclic molecules, offering a protected indole scaffold for targeted functionalization. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and CNS-targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that leverage the indole structure.
• Organic Synthesis Building Block: Provides a versatile, protected indole core for constructing complex heterocyclic libraries in medicinal chemistry and material science.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	3-Bromo-2-Methylindole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	775305-12-9
Molecular Formula	C₁₄H₁₆BrNO₂
Molecular Weight	310.19 g/mol
Synonyms	tert-Butyl 3-bromo-2-methyl-1H-indole-1-carboxylate; 1H-Indole-1-carboxylic acid, 3-bromo-2-methyl-, 1,1-dimethylethyl ester; 3-Bromo-2-methylindole-1-carboxylic acid 1,1-dimethylethyl ester; 3-Bromo-2-methyl-1H-indole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-bromo-2-methylindole; Boc-3-Bromo-2-methylindole
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Methylindole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep container tightly sealed under an inert atmosphere for long-term storage to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.