Description

(E)-7-Chloro-1,2-Dihydrocyclopenta[B]Indol-3(4H)-One Oxime is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel therapeutic agents, offering a precise building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting oncology, neurology, and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drugs and investigational new chemical entities (NCEs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in multi-step synthetic routes for the production of complex Active Pharmaceutical Ingredients (APIs), particularly those with indole-based core structures.
• Biochemical Research: Employed as a tool compound in biochemical assays and for probing biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	(E)-7-Chloro-1,2-Dihydrocyclopenta[B]Indol-3(4H)-One Oxime
CAS No.	774593-85-0
Molecular Formula	C11H9ClN2O
Molecular Weight	220.66 g/mol
Synonyms	(E)-7-Chloro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-one oxime; 7-Chloro-1,2-dihydro-3H-cyclopenta[b]indol-3-one, oxime; 7-Chloro-1,2-dihydrocyclopenta[b]indol-3(4H)-one oxime; (E)-7-Chloro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-one oxime; 774593-85-0; (E)-7-Chloro-1,2-dihydrocyclopenta[b]indol-3(4H)-one oxime; 7-Chloro-1,2-dihydro-3H-cyclopenta[b]indol-3-one oxime
EINECS	Contact for details

Quality Control

Our (E)-7-Chloro-1,2-Dihydrocyclopenta[B]Indol-3(4H)-One Oxime is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring material suitable for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.