Description

6-Bromotryptophan Methyl Ester is a specialized brominated tryptophan derivative that serves as a critical chiral building block in advanced organic synthesis. This compound is valued for its role in introducing the indole moiety with a bromine handle, enabling further functionalization via cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel bioactive molecules, including peptide mimetics, enzyme inhibitors, and complex natural product analogs.

Application

• Key intermediate in the synthesis of complex pharmaceutical compounds and active pharmaceutical ingredients (APIs).
• Chiral building block for constructing non-natural amino acids and modified peptides with enhanced biological properties.
• Precursor in medicinal chemistry for the development of serotonin receptor modulators and other neuroactive agents.
• Starting material for synthesizing fluorescent probes and biochemical tools used in life science research.
• Intermediate in the preparation of agrochemicals and other fine chemicals requiring a functionalized indole scaffold.
• Used in academic and industrial R&D for exploring new catalytic cross-coupling methodologies.

Basic Information

Product Name	6-Bromotryptophan Methyl Ester
CAS No.	774181-71-4
Molecular Formula	C₁₃H₁₅BrN₂O₂
Molecular Weight	311.18 g/mol
Synonyms	Methyl (S)-2-amino-3-(6-bromo-1H-indol-3-yl)propanoate; L-6-Bromotryptophan methyl ester; (S)-Methyl 2-amino-3-(6-bromo-1H-indol-3-yl)propanoate; 6-Bromo-L-tryptophan methyl ester; 6-Bromo-Trp-OMe; 6-Br-Trp-OMe; 6-Bromotryptophan O-methyl ester; 6-Bromoindole-3-alanine methyl ester
EINECS	Contact for details

Quality Control

Our 6-Bromotryptophan Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical assay, and impurity profile. We adhere to relevant industry standards for fine chemical intermediates, and custom synthesis to meet specific purity or grade requirements is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.