Description

8-Chloro-4H-Thieno[3,2-C]Chromene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its unique thienochromene core.
• Research & Development (R&D): Essential for academic and industrial research laboratories exploring new heterocyclic compounds and their biological activities.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	8-Chloro-4H-Thieno[3,2-C]Chromene-2-Carboxylic Acid
CAS No.	773873-20-4
Molecular Formula	C₁₂H₇ClO₃S
Molecular Weight	266.70 g/mol
Synonyms	8-Chloro-4H-thieno[3,2-c]chromene-2-carboxylic acid; 8-Chloro-2-carboxy-4H-thieno[3,2-c]chromene; 8-Chloro-4H-thieno[3,2-c]chromene-2-carboxylic acid; 773873-20-4; Thieno[3,2-c]chromene-2-carboxylic acid, 8-chloro-4H-; 8-Chloro-4H-thienochromene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Chloro-4H-Thieno[3,2-C]Chromene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed due to the compound's sensitivity to light and potential moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.