Description

2-Bromo-4-Fluorothiophenol is a high-purity organosulfur building block characterized by its reactive thiol (-SH) group and halogen substituents. This compound is essential for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research and development. It serves as a critical intermediate for medicinal chemists and material scientists working on novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides requiring fluorinated and sulfur-containing motifs.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands in catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Biology Probes: Used to modify peptides, proteins, and other biomolecules for study and diagnostic applications.

Basic Information

Product Name	2-Bromo-4-Fluorothiophenol
CAS No.	773853-92-2
Molecular Formula	C6H4BrFS
Molecular Weight	207.06 g/mol
Synonyms	4-Fluoro-2-bromothiophenol; 2-Bromo-4-fluorobenzenethiol; 1-Bromo-3-fluoro-2-mercaptobenzene; 2-Bromo-4-fluorophenyl mercaptan; (2-Bromo-4-fluorophenyl)thiol; Benzenethiol, 2-bromo-4-fluoro-; 773853-92-2
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorothiophenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere to prevent oxidation of the thiol group. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.