Description

3-(4-Benzyloxy-1H-Indol-3-Yl)-Acrylic Acid CAS NO 773133-37-2 is a high-purity, functionalized indole derivative featuring an acrylic acid moiety, serving as a critical advanced intermediate in organic synthesis. Its molecular architecture makes it a valuable building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used in coupling reactions, such as amide bond formation or esterification, to introduce the indole-acrylate scaffold into larger molecular frameworks.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize the biological activity of indole-based compounds.
• Chemical Reference Standard: Serves as an analytical standard for quality control and method development in laboratories manufacturing or researching similar compounds.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and plant growth regulators.

Basic Information

Product Name	3-(4-Benzyloxy-1H-Indol-3-Yl)-Acrylic Acid
CAS No.	773133-37-2
Molecular Formula	C18H15NO3
Molecular Weight	293.32 g/mol
Synonyms	3-(4-Benzyloxy-1H-indol-3-yl)prop-2-enoic acid; (E)-3-(4-(Benzyloxy)-1H-indol-3-yl)acrylic acid; 4-Benzyloxyindole-3-acrylic acid; 3-(4-Benzyloxyindol-3-yl)acrylic acid; BOC Sciences Brand Name: BBL-B-003; 3-(4-Benzyloxy-1H-indol-3-yl)-2-propenoic acid; 2-Propenoic acid, 3-(4-(phenylmethoxy)-1H-indol-3-yl)-
EINECS	Contact for details

Quality Control

Our 3-(4-Benzyloxy-1H-Indol-3-Yl)-Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.