Description

3-(5-Fluoro-1H-Indol-3-Yl)-Acrylic Acid is a high-purity fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which incorporates both an indole ring and an acrylic acid moiety, enabling its use in the development of novel pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, or plant growth regulators that leverage the fluorinated indole structure.
• Biochemical Probe Synthesis: Utilized in the design and creation of fluorescent probes or enzyme inhibitors for biological pathway analysis.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	3-(5-Fluoro-1H-Indol-3-Yl)-Acrylic Acid
CAS No.	773130-49-7
Molecular Formula	C11H8FNO2
Molecular Weight	205.19 g/mol
Synonyms	(E)-3-(5-Fluoro-1H-indol-3-yl)acrylic acid; 3-(5-Fluoro-1H-indol-3-yl)-2-propenoic acid; 5-Fluoro-3-indoleacrylic acid; trans-3-(5-Fluoroindol-3-yl)acrylic acid; 3-(5-Fluoroindol-3-yl)propenoic acid; 773130-49-7; 5-Fluoroindole-3-acrylic acid
EINECS	Contact for details

Quality Control

Our 3-(5-Fluoro-1H-Indol-3-Yl)-Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.