Description

3-Amino-3-(1-Methyl-Indol-3-Yl)-Propionic Acid is a specialized non-proteinogenic amino acid derivative featuring an indole moiety. This compound is of significant interest in pharmaceutical research and development, particularly as a sophisticated building block for novel drug candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of complex molecules targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Peptidomimetics & Bioactive Molecule Synthesis: Serves as a constrained amino acid analog for constructing peptide mimics and other bioactive compounds with enhanced metabolic stability and receptor selectivity.
• Medicinal Chemistry Research: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies to explore novel chemical space.
• Bioconjugation & Probe Development: The amino and carboxylic acid functional groups allow for conjugation to carriers, labels, or other molecules to create research tools and diagnostic probes.
• Academic & Institutional R&D: Employed in university and government laboratories for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	3-Amino-3-(1-Methyl-Indol-3-Yl)-Propionic Acid
CAS No.	773124-24-6
Molecular Formula	C₁₄H₁₆N₂O₂
Molecular Weight	244.29 g/mol
Synonyms	3-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid; β-(1-Methylindol-3-yl)-β-alanine; 3-(1-Methyl-1H-indol-3-yl)-3-aminopropionic acid; (R/S)-3-Amino-3-(1-methylindol-3-yl)propionic acid; 1-Methyl-3-(2-carboxyethyl)indole-3-amine; DL-3-Amino-3-(1-methylindol-3-yl)propanoic acid; 3-(1-Methyl-1H-indol-3-yl)-β-alanine
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(1-Methyl-Indol-3-Yl)-Propionic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and MS. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for early-phase development. Specifications are designed to meet the high standards required for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.