Description

3-Amino-3-(5-Methoxy-Indol-3-Yl)-Propionic Acid is a specialized indole derivative and a non-proteinogenic amino acid of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block for the development of complex pharmaceutical intermediates and bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery programs and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurological and oncological therapeutic areas.
• Peptidomimetics Research: Used in the design and synthesis of peptidomimetics and constrained peptides due to its unique indole and amino acid backbone structure.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries to identify new drug candidates.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and as a probe for investigating biological pathways involving tryptophan metabolism.
• Asymmetric Synthesis: Utilized as a starting material or catalyst in asymmetric synthesis to introduce chirality into target molecules.

Basic Information

Product Name	3-Amino-3-(5-Methoxy-Indol-3-Yl)-Propionic Acid
CAS No.	773122-10-4
Molecular Formula	C₁₂H₁₄N₂O₃
Molecular Weight	234.25 g/mol
Synonyms	3-Amino-3-(5-methoxy-1H-indol-3-yl)propanoic acid; 3-(5-Methoxy-1H-indol-3-yl)-3-aminopropanoic acid; 5-Methoxy-DL-tryptophan; β-Amino-β-(5-methoxy-3-indolyl)propionic acid; (RS)-3-Amino-3-(5-methoxyindol-3-yl)propionic acid; DL-5-Methoxytryptophan; 5-Methoxy-DL-Trp
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(5-Methoxy-Indol-3-Yl)-Propionic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.