Description

4-Bromobenzonitrile-D4 is a deuterium-labeled analog of 4-bromobenzonitrile, a valuable building block in synthetic organic chemistry. This isotopically labeled compound is essential for creating internal standards in quantitative mass spectrometry, ensuring accurate and reliable analytical results. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry industries for drug metabolism studies, pharmacokinetics, and environmental fate analysis.

Application

• As a deuterated internal standard for the precise quantification of 4-bromobenzonitrile and related metabolites in LC-MS/MS and GC-MS analysis.
• In pharmaceutical research for drug discovery and development, particularly in studies of absorption, distribution, metabolism, and excretion (ADME).
• For metabolite identification and profiling in preclinical and clinical studies to understand biotransformation pathways.
• In environmental analysis to trace and quantify brominated aromatic compounds and their degradation products.
• As a specialized synthetic intermediate in the preparation of other deuterium-labeled complex molecules for research purposes.
• For quality control and method validation in analytical laboratories to meet regulatory compliance standards (e.g., FDA, EMA).

Basic Information

Product Name	4-Bromobenzonitrile-D4
CAS No.	771534-56-6
Molecular Formula	C7D4BrN
Molecular Weight	186.04 g/mol
Synonyms	4-Bromo-2,3,5,6-tetradeuteriobenzonitrile; p-Bromobenzonitrile-d4; 4-Bromobenzonitrile (phenyl-d4); 1-Bromo-4-cyanobenzene-d4; 4-Cyanobromobenzene-d4; p-Cyanobromobenzene-d4; (2,3,5,6-Tetradeuterio-4-bromophenyl)cyanide
EINECS	Contact for details

Quality Control

Our 4-Bromobenzonitrile-D4 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm isotopic purity and chemical identity. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data on chemical purity, isotopic enrichment, and solvent residues. Our quality systems are designed to support GLP/GMP compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.