Description

3-Thiophenecarboxamide, 2-[[2-(3,4-Dimethoxyphenyl)Acetyl]Amino]- is a high-purity synthetic organic compound featuring a thiophene carboxamide core linked to a dimethoxyphenylacetyl group. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for research in medicinal chemistry. It is primarily sought by pharmaceutical R&D and fine chemical synthesis sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged scaffold.
• Biochemical Reagent: Serves as a substrate or inhibitor in enzymatic assays and biochemical pathway studies.
• Organic Synthesis: A versatile precursor for constructing more complex heterocyclic compounds and functionalized thiophene derivatives.
• Material Science Research: Investigated as a monomer or dopant for conductive polymers and organic electronic materials.

Basic Information

Product Name	3-Thiophenecarboxamide, 2-[[2-(3,4-Dimethoxyphenyl)Acetyl]Amino]-
CAS No.	771503-50-5
Molecular Formula	C15H16N2O4S
Molecular Weight	320.36 g/mol
Synonyms	2-[(2-(3,4-Dimethoxyphenyl)acetyl)amino]-3-thiophenecarboxamide; N-[2-(3,4-Dimethoxyphenyl)acetyl]-2-aminothiophene-3-carboxamide; 2-Amino-N-[2-(3,4-dimethoxyphenyl)acetyl]thiophene-3-carboxamide; 771503-50-5; Verubecestat intermediate; BACE1 inhibitor intermediate; Thiophene-3-carboxamide derivative
EINECS	Contact for details

Quality Control

Our production of 3-Thiophenecarboxamide, 2-[[2-(3,4-Dimethoxyphenyl)Acetyl]Amino]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We operate under a cGMP-compliant quality management system to meet the exacting standards of the pharmaceutical supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.