Description

2-[1,4]Diazepan-1-Yl-1-(4-Fluoro-Benzyl)-1H-Benzoimidazole is a sophisticated benzimidazole derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a versatile pharmaceutical intermediate in the research and development of new therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of potential drug candidates targeting a range of diseases.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its benzimidazole and diazepane pharmacophores.
• Biochemical Tool Compound: Serves as a reference standard or a probe in biochemical assays to study enzyme inhibition or receptor binding.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for preclinical and clinical trial material.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.

Basic Information

Product Name	2-[1,4]Diazepan-1-Yl-1-(4-Fluoro-Benzyl)-1H-Benzoimidazole
CAS No.	770690-79-4
Molecular Formula	C19H21FN4
Molecular Weight	324.40 g/mol
Synonyms	1-(4-Fluorobenzyl)-2-(1,4-diazepan-1-yl)-1H-benzimidazole; 1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]-2-(1,4-diazepan-1-yl)-; 2-(1,4-Diazepan-1-yl)-1-(4-fluorobenzyl)-1H-benzimidazole; 770690-79-4; Benzimidazole diazepane derivative; 4-Fluoro-benzyl benzimidazole diazepane
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.