Description

2H-Indole-2-Carboxylicacid,3,3A,4,5,6,7-Hexahydro-,(2S-Trans)-(9Ci) is a high-purity, stereochemically defined indole derivative that serves as a critical chiral building block in advanced organic synthesis. Its rigid, fused bicyclic structure and defined stereochemistry make it an invaluable intermediate for constructing complex molecules with high precision. This compound is primarily sought after by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, including potential therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the construction of complex molecules for next-generation herbicides, fungicides, and insecticides requiring specific stereochemistry.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or probe in the study of biological pathways and protein interactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development in synthetic organic chemistry.
• Fine Chemical Production: An intermediate in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	2H-Indole-2-Carboxylicacid,3,3A,4,5,6,7-Hexahydro-,(2S-Trans)-(9Ci)
CAS No.	770685-87-5
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2S)-3,3a,4,5,6,7-Hexahydro-2H-indole-2-carboxylic acid; (2S-trans)-Hexahydro-2H-indole-2-carboxylic acid; (2S)-Octahydroindole-2-carboxylic acid; (2S)-2-Carboxyhexahydroindole; cis-(2S,3aS)-Octahydroindole-2-carboxylic acid; L-Octahydroindole-2-carboxylic acid; (S)-2-Carboxyhexahydroindole; 770685-87-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with quality documentation suitable for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is stable under these conditions but should be kept away from strong acids and oxidizing agents. For long-term storage, consider inert atmosphere packaging to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.