Description

6,7-Dimethoxy-1-((E)-Propenyl)-3,4-Dihydro-Isoquinoline is a high-purity, advanced pharmaceutical intermediate belonging to the isoquinoline class of heterocyclic compounds. Its value lies in its role as a critical building block for the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. This compound is essential for pharmaceutical manufacturers and R&D organizations focused on developing new therapeutic agents, especially within the fields of neurology and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new biologically active compounds.
• Alkaloid Synthesis: Used in the laboratory-scale preparation of complex tetrahydroisoquinoline alkaloids and their analogs for biological screening.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Fundamental building block in organic synthesis projects within university laboratories and corporate R&D centers.

Basic Information

Product Name	6,7-Dimethoxy-1-((E)-Propenyl)-3,4-Dihydro-Isoquinoline
CAS No.	770661-64-8
Molecular Formula	C₁₄H₁₇NO₂
Molecular Weight	231.29 g/mol
Synonyms	1-[(1E)-Prop-1-en-1-yl]-6,7-dimethoxy-3,4-dihydroisoquinoline; (E)-1-(Prop-1-en-1-yl)-6,7-dimethoxy-3,4-dihydroisoquinoline; 6,7-Dimethoxy-1-[(E)-1-propenyl]-1,2,3,4-tetrahydroisoquinoline; 1-(1-Propenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline (E-isomer); Tetrahydroisoquinoline Derivative CAS 770661-64-8; 6,7-Dimethoxy-1-(trans-propenyl)-3,4-dihydroisoquinoline
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1-((E)-Propenyl)-3,4-Dihydro-Isoquinoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.