Description

6,7-Dimethoxy-1(S)-[2-[4-(Trifluoromethyl)Phenyl]Ethyl]-1,2,3,4-Tetrahydroisoquinoline is a high-purity, chiral tetrahydroisoquinoline derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated pharmaceutical intermediate and key building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential therapeutic agents, particularly for central nervous system (CNS) targets.
• Drug Discovery & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Research: Acts as a building block for developing novel crop protection agents and pesticides.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and ligands for catalysis.
• Biochemical Research: Utilized as a tool compound in biochemical assays and for probing biological pathways.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	6,7-Dimethoxy-1(S)-[2-[4-(Trifluoromethyl)Phenyl]Ethyl]-1,2,3,4-Tetrahydroisoquinoline
CAS No.	769172-81-8
Molecular Formula	C20H22F3NO2
Molecular Weight	365.39 g/mol
Synonyms	1(S)-[2-[4-(Trifluoromethyl)Phenyl]Ethyl]-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline; (S)-6,7-Dimethoxy-1-(2-(4-(trifluoromethyl)phenyl)ethyl)-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1-[(S)-2-[4-(trifluoromethyl)phenyl]ethyl]-1,2,3,4-tetrahydroisoquinoline; 769172-81-8; Tetrahydroisoquinoline derivative with trifluoromethylphenyl group; Chiral tetrahydroisoquinoline building block
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1(S)-[2-[4-(Trifluoromethyl)Phenyl]Ethyl]-1,2,3,4-Tetrahydroisoquinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.