Description

Amino-4,4-Difluoro-Cyclohexaneacetic Acid is a high-value, functionalized cyclohexane derivative featuring both amino and difluoro substituents. This compound is a critical pharmaceutical intermediate and building block for the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate its unique fluorinated and carboxylic acid functionalities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting metabolic and central nervous system diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the difluoro group can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics & Bio-conjugation: The amino and carboxylic acid groups make it suitable for constructing peptide analogs and for bio-conjugation applications in drug delivery systems.
• Material Science Research: Employed in the development of specialty polymers and functional materials that require fluorinated monomers for specific properties like chemical resistance.
• Chemical Biology Probes: Useful for synthesizing fluorescent probes or affinity tags to study biological processes and protein interactions.

Basic Information

Product Name	Amino-4,4-Difluoro-Cyclohexaneacetic Acid
CAS No.	769169-46-2
Molecular Formula	C8H13F2NO2
Molecular Weight	193.19 g/mol
Synonyms	4-Amino-4,4-difluorocyclohexaneacetic Acid; 4-Amino-4,4-difluorocyclohexylacetic Acid; 2-(4-Amino-4,4-difluorocyclohexyl)acetic Acid; 4,4-Difluoro-4-aminocyclohexylacetic Acid; 4-Amino-4,4-difluorocyclohexane-1-acetic Acid; (4-Amino-4,4-difluorocyclohexyl)acetic Acid; 769169-46-2; Amino difluorocyclohexaneacetic acid
EINECS	Contact for details

Quality Control

Our Amino-4,4-Difluoro-Cyclohexaneacetic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practice (GMP) principles where applicable. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, available upon request. We are committed to meeting the stringent requirements of pharmaceutical and research customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.