Description

Fumaric-2,3-13C2 Acid is a stable isotope-labeled analog of fumaric acid, where two carbon atoms at the 2 and 3 positions are replaced with the carbon-13 isotope. This compound is essential for advanced research and analytical applications requiring precise molecular tracing and quantification. It is primarily utilized by scientists and manufacturers in the fields of pharmaceutical development, metabolic pathway analysis, and high-end analytical chemistry.

Application

• Isotope-Labeled Internal Standards for accurate quantification in mass spectrometry (LC-MS, GC-MS).
• Metabolic Flux Analysis and tracer studies to investigate cellular metabolism and biochemical pathways.
• Pharmaceutical Research, including the development and pharmacokinetic study of drug candidates.
• NMR Spectroscopy as a carbon-13 enriched standard for structural elucidation and method validation.
• Biochemical Research for studying enzyme mechanisms, particularly those involving fumarase and the citric acid cycle.
• Quality Control in the production of other labeled compounds and fine chemicals.

Basic Information

Product Name	Fumaric-2,3-13C2 Acid
CAS No.	769108-94-3
Molecular Formula	C4H4O4 (with 13C at positions 2 & 3)
Molecular Weight	118.06 g/mol (approx.)
Synonyms	(2,3-13C2)Fumaric Acid; Fumaric Acid-2,3-13C2; 13C2-Fumaric Acid; (E)-But-2-enedioic-2,3-13C2 Acid; Allomaleic-2,3-13C2 Acid; Boletic-2,3-13C2 Acid; trans-1,2-Ethylenedicarboxylic-2,3-13C2 Acid; Isotopically Labeled Fumaric Acid
EINECS	Contact for details

Quality Control

Our Fumaric-2,3-13C2 Acid is produced and handled under strict quality management systems to ensure the highest isotopic and chemical purity for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical results. We adhere to relevant standards for high-purity reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The product is hygroscopic (moisture-sensitive) and should be kept under inert conditions when not in use to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom % (at positions 2 & 3)
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.