Description

Phosphonic Acid, (3-Methyloxiranyl)-, Monomethyl Ester, trans-(-)- (9Ci) is a specialized organophosphorus compound featuring a reactive epoxide (oxirane) ring. This unique structure makes it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor for synthesizing novel drug candidates, particularly those targeting specific biological pathways.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators with enhanced activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphonate-based ligands used in asymmetric catalysis.
• Material Science Research: Employed in the development of functional polymers, coatings, or additives where the phosphonate and epoxide groups impart specific properties.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme mechanisms or cellular processes.

Basic Information

Product Name	Phosphonic Acid, (3-Methyloxiranyl)-, Monomethyl Ester, trans-(-)- (9Ci)
CAS No.	763886-65-3
Molecular Formula	C5H11O4P
Molecular Weight	166.11 g/mol
Synonyms	trans-(-)-Methyl (3-Methyloxiran-2-yl)phosphonate; (-)-(2R,3R)-Methyl 2-Methyl-3-oxiranephosphonate; Methyl trans-(-)-2-Methyl-3-oxiranephosphonate; (2R,3R)-(-)-Methyl 2-Methyloxirane-2-phosphonate; Phosphonic acid, P-[(2R,3R)-2-methyloxiranyl]-, methyl ester; Chiral Epoxy Methyl Phosphonate; (R,R)-Methyl Glycidyl Phosphonate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, which is critical for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the epoxide functionality and light-sensitive nature indicated, prolonged exposure to light or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.