Description

5-Thiophen-2-Yl-Isoxazole-3-Carboxylic Acid CAS NO 763109-71-3 is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique molecular architecture, combining thiophene and isoxazole rings, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by pharmaceutical R&D and agrochemical laboratories for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in areas requiring heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its bioactive heterocyclic core.
• Material Science Research: Serves as a precursor for functionalized polymers or organic electronic materials due to the thiophene moiety.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and heterocyclic compound synthesis.
• Custom Synthesis Building Block: Provides a specialized starting point for custom manufacturing and scale-up projects in fine chemicals.

Basic Information

Item	Detail
Product Name	5-Thiophen-2-Yl-Isoxazole-3-Carboxylic Acid
CAS No.	763109-71-3
Molecular Formula	C8H5NO3S
Molecular Weight	195.20 g/mol
Synonyms	5-(Thiophen-2-yl)isoxazole-3-carboxylic acid; 5-(2-Thienyl)-3-isoxazolecarboxylic Acid; 2-Thiophen-2-yl-[1,2]oxazole-5-carboxylic acid; 5-(Thien-2-yl)isoxazole-3-carboxylic acid; 763109-71-3; AI3-52362; STK387166; Thiophene-isoxazole carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our production of 5-Thiophen-2-Yl-Isoxazole-3-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is compatible with strong acids and organic solvents but should be kept separate from strong bases and oxidizing agents. Keep the container tightly sealed when not in use to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.