Description

1-Chloroisoquinoline-5-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its unique molecular structure, featuring both a carboxylic acid and a chlorinated isoquinoline moiety, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with novel modes of action.
• Material Science: Serves as a building block for creating specialized ligands, catalysts, and functional organic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploratory chemistry projects.

Basic Information

Product Name	1-Chloroisoquinoline-5-Carboxylic Acid
CAS No.	763068-68-4
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	5-Carboxy-1-chloroisoquinoline; 1-Chloro-5-isoquinolinecarboxylic Acid; 1-Chloroisoquinoline-5-carboxylic acid; Isoquinoline-5-carboxylic acid, 1-chloro-; 763068-68-4; 1-Chloro-5-carboxyisoquinoline; 5-(Carboxy)-1-chloroisoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloroisoquinoline-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.