Description

Methyl 5-Fluoro-2-Methylindole-3-Carboxylate is a high-purity fluorinated indole derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules with targeted biological activity. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly in oncology and CNS research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in developing new active ingredients for crop protection with potential fungicidal or herbicidal properties.
• Material Science: Serves as a precursor for specialty polymers and organic electronic materials due to its fused heterocyclic structure.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs exploring structure-activity relationships (SAR).
• Fluorine Chemistry: Utilized in studies investigating the effects of fluorine substitution on the pharmacokinetics and metabolic stability of lead compounds.

Basic Information

Product Name	Methyl 5-Fluoro-2-Methylindole-3-Carboxylate
CAS No.	762288-10-8
Molecular Formula	C11H10FNO2
Molecular Weight	207.20 g/mol
Synonyms	Methyl 5-Fluoro-2-methyl-1H-indole-3-carboxylate; 5-Fluoro-2-methylindole-3-carboxylic acid methyl ester; 1H-Indole-3-carboxylic acid, 5-fluoro-2-methyl-, methyl ester; 762288-10-8; 5-Fluoro-2-methyl-1H-indole-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Fluoro-2-Methylindole-3-Carboxylate adheres to stringent quality management protocols. Every batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identity confirmation, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.