Description

2-(4-Trifluoromethyl-Phenyl)-Thiazole-5-Carboxylic Acid is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where the trifluoromethyl and thiazole moieties impart desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas like oncology, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole ring.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating specialty polymers and advanced organic materials with unique electronic or surface properties.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Utilized as a core structure for creating fluorescent tags or molecular probes to study biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-(4-Trifluoromethyl-Phenyl)-Thiazole-5-Carboxylic Acid
CAS No.	762287-51-4
Molecular Formula	C11H6F3NO2S
Molecular Weight	273.23 g/mol
Synonyms	5-Thiazolecarboxylic acid, 2-[4-(trifluoromethyl)phenyl]-; 2-(4-(Trifluoromethyl)phenyl)thiazole-5-carboxylic acid; 2-(4-Trifluoromethylphenyl)-1,3-thiazole-5-carboxylic acid; 2-(p-Trifluoromethylphenyl)thiazole-5-carboxylic acid; 762287-51-4; 2-(4-Trifluoromethylphenyl)thiazole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Trifluoromethyl-Phenyl)-Thiazole-5-Carboxylic Acid undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system is designed to meet the stringent requirements of research and industrial-scale applications. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profiles are provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.