Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methylpropyl Ester, (1R,2R,4R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid bicyclic framework and defined stereochemistry make it a valuable precursor for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis, catalyst development, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the specific stereochemistry can influence biological activity and environmental selectivity.
• Catalyst and Ligand Development: Acts as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric transformations to create enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require rigid, functionalized monomers.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry, enabling the exploration of new synthetic routes and reaction mechanisms.
• Flavor and Fragrance Industry: Potential use as an intermediate for synthesizing complex, stereochemically defined odorants and flavor compounds.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methylpropyl Ester, (1R,2R,4R)- (9Ci)
CAS No.	762261-09-6
Molecular Formula	C12H18O2
Molecular Weight	194.27 g/mol
Synonyms	(1R,2R,4R)-2-Methylpropyl bicyclo[2.2.1]hept-5-ene-2-carboxylate; (1R,2R,4R)-Isobutyl 5-norbornene-2-carboxylate; (1R,2R,4R)-endo-Isobutyl 5-norbornene-2-carboxylate; (1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid isobutyl ester; (1R,2R,4R)-Isobutyl 2-norbornene-5-carboxylate; endo-(1R,2R,4R)-Isobutyl 5-norbornene-2-carboxylate; Chiral Isobutyl Norbornene Carboxylate
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methylpropyl Ester, (1R,2R,4R)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, GC, and NMR spectroscopy, to confirm identity, enantiomeric excess (ee), and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.