Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Butyl Ester, (1R,2R,4R)- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex, biologically active molecules, offering precise control over the three-dimensional architecture of target compounds. Pharmaceutical, agrochemical, and advanced material researchers need it for developing novel active ingredients, catalysts, and specialty polymers where stereochemical integrity is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of stereoselective pesticides and herbicides, where the specific enantiomer can dictate biological activity and environmental profile.
• Catalyst & Ligand Development: Serves as a precursor for constructing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Research: Employed in the creation of specialty polymers and functional materials with tailored optical or mechanical properties derived from its rigid norbornene core.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic chemistry and for scaling up stereoselective synthetic routes in process development.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Butyl Ester, (1R,2R,4R)- (9Ci)
CAS No.	762261-08-5
Molecular Formula	C13H20O2
Molecular Weight	208.30 g/mol
Synonyms	(1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid butyl ester; (1R,2R,4R)-endo-5-Norbornene-2-carboxylic Acid Butyl Ester; (-)-endo-Bicyclo[2.2.1]hept-5-ene-2-carboxylic Acid Butyl Ester; Butyl (1R,2R,4R)-bicyclo[2.2.1]hept-5-ene-2-carboxylate; endo-(-)-5-Norbornene-2-carboxylic Acid Butyl Ester; Chiral Norbornene Ester; (1R,2R,4R)-endo-NBCOOBu
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Butyl Ester, (1R,2R,4R)- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Products undergo rigorous analytical testing, including chiral HPLC, NMR, and GC, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.