Description

1H-Benzimidazole-2-Methanamine, 4,5,6,7-Tetrahydro-n-Methyl- is a specialized, high-purity heterocyclic amine derivative of tetrahydrobenzimidazole, serving as a critical advanced intermediate in modern organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific structural motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation fungicides, herbicides, and plant growth regulators that require the benzimidazole scaffold for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and production of advanced polymers, dyes, and photoactive materials.
• Chemical Biology Probes: Utilized to develop molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1H-Benzimidazole-2-Methanamine, 4,5,6,7-Tetrahydro-n-Methyl-
CAS No.	762224-66-8
Molecular Formula	C9H15N3
Molecular Weight	165.24 g/mol
Synonyms	N-Methyl-4,5,6,7-tetrahydro-1H-benzimidazol-2-ylmethanamine; 2-(Aminomethyl)-N-methyl-4,5,6,7-tetrahydro-1H-benzimidazole; (N-Methyl-4,5,6,7-tetrahydro-1H-benzimidazol-2-yl)methanamine; 4,5,6,7-Tetrahydro-N-methyl-1H-benzimidazole-2-methanamine; Tetrahydro-N-methylbenzimidazolemethanamine; 762224-66-8; 1H-Benzimidazole-2-methanamine, 4,5,6,7-tetrahydro-N-methyl-
EINECS	Contact for details

Quality Control

Our production of 1H-Benzimidazole-2-Methanamine, 4,5,6,7-Tetrahydro-n-Methyl- adheres to stringent quality management systems. The material is manufactured under controlled conditions and undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure batch-to-batch consistency and high purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.