Description

1H-Pyrazole-5-Carboxamide, 1-(Chloroacetyl)-4,5-Dihydro-, (5S)- (9Ci) is a high-purity, chiral pyrazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical synthetic intermediate, valued for its reactive chloroacetyl group and defined stereochemistry, which enable precise molecular construction. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active ingredients and complex specialty molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of chiral drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where its pyrazole core contributes to biological activity.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Chemical Biology Probes: Utilized as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring high stereochemical purity and reliable reactivity.

Basic Information

Product Name	1H-Pyrazole-5-Carboxamide, 1-(Chloroacetyl)-4,5-Dihydro-, (5S)- (9Ci)
CAS No.	761414-85-1
Molecular Formula	C6H8ClN3O2
Molecular Weight	189.60 g/mol
Synonyms	(5S)-1-(Chloroacetyl)-4,5-dihydro-1H-pyrazole-5-carboxamide; 1-(Chloroacetyl)-4,5-dihydro-(5S)-1H-pyrazole-5-carboxamide; (S)-1-(Chloroacetyl)-4,5-dihydro-1H-pyrazole-5-carboxamide; 761414-85-1; 1H-Pyrazole-5-carboxamide, 1-(chloroacetyl)-4,5-dihydro-, (5S)-; (5S)-1-(2-Chloroacetyl)-4,5-dihydro-1H-pyrazole-5-carboxamide
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-5-Carboxamide, 1-(Chloroacetyl)-4,5-Dihydro-, (5S)- (9Ci) adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like HPLC, NMR, and chiral analysis to ensure identity, purity, and enantiomeric excess meet exacting standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.