Description

Methyl 1-(4-Chlorobenzyl)-1H-Indole-3-Carboxylate is a high-purity, synthetically valuable indole derivative. This compound serves as a crucial advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) based on the indole scaffold.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of more complex heterocyclic compounds.
• Biochemical Research: May be utilized as a reference standard or probe in biochemical assays to study enzyme interactions or receptor binding.
• Process Development & Scale-Up: Employed in the optimization and pilot-scale production of active pharmaceutical ingredients (APIs) for clinical trials.

Basic Information

Product Name	Methyl 1-(4-Chlorobenzyl)-1H-Indole-3-Carboxylate
CAS No.	761402-59-9
Molecular Formula	C17H14ClNO2
Molecular Weight	299.75 g/mol
Synonyms	1-[(4-Chlorophenyl)methyl]-1H-indole-3-carboxylic acid methyl ester; Methyl 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxylate; 1-(4-Chlorobenzyl)indole-3-carboxylic acid methyl ester; 1H-Indole-3-carboxylic acid, 1-[(4-chlorophenyl)methyl]-, methyl ester; 761402-59-9
EINECS	Contact for details

Quality Control

Our Methyl 1-(4-Chlorobenzyl)-1H-Indole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.