Description

Bicyclo[2.2.2]Octan-2-Ol, 3-(Methylamino)-, trans- (9Ci) is a specialized bicyclic amino alcohol building block of significant interest in advanced organic synthesis. This compound matters for its rigid, three-dimensional scaffold, which is highly valuable for constructing complex molecular architectures with defined stereochemistry. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, chiral ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system.
• Chiral Ligand/ Catalyst Precursor: Used in the synthesis of sophisticated ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides that require a rigid, sterically defined core structure.
• Material Science Monomer: Potential use in the synthesis of specialty polymers and dendrimers with unique thermal and mechanical properties.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and receptor interactions due to its constrained geometry.

Basic Information

Product Name	Bicyclo[2.2.2]Octan-2-Ol, 3-(Methylamino)-, trans- (9Ci)
CAS No.	761340-30-1
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	trans-3-(Methylamino)bicyclo[2.2.2]octan-2-ol; 3-(Methylamino)-bicyclo[2.2.2]octan-2-ol, trans-; Bicyclo[2.2.2]octan-2-ol, 3-(methylamino)-, (2R,3S)-rel-; (rel-2R,3S)-3-(Methylamino)bicyclo[2.2.2]octan-2-ol; 2-Bicyclo[2.2.2]octanol, 3-(methylamino)-, trans-; Amino alcohol building block 761340-30-1
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octan-2-Ol, 3-(Methylamino)-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.