Description

(R)-3-Amino-3-(3-Thienyl)-Propionic Acid CAS NO 760941-22-8 is a high-purity, non-proteinogenic amino acid derivative featuring a thiophene ring, serving as a critical chiral building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for the research and development of novel pharmaceuticals, particularly in the creation of active pharmaceutical ingredients (APIs) and chiral ligands. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis: Used as a building block for constructing complex, enantiomerically pure molecules in medicinal chemistry and process R&D.
• Peptidomimetics Development: Incorporated into peptide analogs to enhance metabolic stability and bioavailability of therapeutic peptides.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complex formation.
• Agrochemical Research: Employed in the development of new, enantioselective pesticides and herbicides.
• Academic & Institutional Research: A valuable reagent for studying structure-activity relationships (SAR) and novel synthetic methodologies in university and corporate labs.

Basic Information

Product Name	(R)-3-Amino-3-(3-Thienyl)-Propionic Acid
CAS No.	760941-22-8
Molecular Formula	C7H9NO2S
Molecular Weight	171.22 g/mol
Synonyms	(R)-3-Amino-3-(thiophen-3-yl)propanoic acid; (R)-β-Amino-β-(3-thienyl)propionic Acid; (3R)-3-Amino-3-(3-thienyl)propanoic acid; D-3-Amino-3-(3-thienyl)propionic acid; (R)-3-Thienyl-β-alanine; (R)-3-(3-Aminopropyl)thiophene-3-carboxylic acid; (R)-3-Amino-3-(thien-3-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-3-(3-Thienyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.