Description

4-(2-(Difluoromethoxy)Phenyl)Thiazol-2-Amine CAS NO 760936-33-2 is a high-value, heterocyclic organic compound featuring a thiazole core substituted with a difluoromethoxyphenyl group. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate for the synthesis of novel active ingredients. It is primarily sought after by research organizations and fine chemical manufacturers engaged in drug discovery and development, particularly within the agrochemical and pharmaceutical sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex molecules in medicinal chemistry and material science research.
• Chemical Reference Standard: Employed as a high-purity standard in analytical laboratories for method development and quality control of related compounds.
• Ligand and Catalyst Development: Investigated for use in the creation of specialized ligands for metal-catalyzed reactions in fine chemical production.

Basic Information

Product Name	4-(2-(Difluoromethoxy)Phenyl)Thiazol-2-Amine
CAS No.	760936-33-2
Molecular Formula	C10H8F2N2OS
Molecular Weight	242.25 g/mol
Synonyms	2-Amino-4-[2-(difluoromethoxy)phenyl]-1,3-thiazole; 4-[2-(Difluoromethoxy)phenyl]-2-thiazolamine; 4-(2-(Difluoromethoxy)phenyl)-1,3-thiazol-2-amine; 2-Thiazolamine, 4-[2-(difluoromethoxy)phenyl]-; 760936-33-2; 4-(2-Difluoromethoxyphenyl)thiazol-2-ylamine
EINECS	Contact for details

Quality Control

Every batch of 4-(2-(Difluoromethoxy)Phenyl)Thiazol-2-Amine is produced under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods like HPLC and GC. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.