Description

1H-Imidazole-2-Methanol,α-(1,1-Dimethylethyl)-(9Ci) is a specialized organic compound belonging to the imidazole class, characterized by its tert-butyl substituted hydroxymethyl side chain. This unique structure makes it a valuable building block (synthon) and key intermediate in advanced organic synthesis, particularly for constructing complex heterocyclic frameworks. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing imidazole or related heterocyclic cores for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of new fungicides, herbicides, and plant growth regulators where the imidazole moiety imparts biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating novel ligands used in coordination chemistry and catalysis, including asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, ionic liquids, and metal-organic frameworks (MOFs) due to its functional groups.
• Chemical Biology & Proteomics: Utilized as a scaffold or modifier in the design of chemical probes, enzyme inhibitors, and bioconjugation reagents.
• Custom Synthesis & Contract Manufacturing: A key raw material for fine chemical and CDMO (Contract Development and Manufacturing Organization) companies producing bespoke compounds for clients.

Basic Information

Product Name	1H-Imidazole-2-Methanol,α-(1,1-Dimethylethyl)-(9Ci)
CAS No.	760177-75-1
Molecular Formula	C8H14N2O
Molecular Weight	154.21 g/mol
Synonyms	2-(tert-Butylhydroxymethyl)imidazole; α-(tert-Butyl)-1H-imidazole-2-methanol; 1H-Imidazole-2-methanol, α-(1,1-dimethylethyl)-; 2-[(2-Methyl-2-propanyl)hydroxymethyl]-1H-imidazole; tert-Butyl(1H-imidazol-2-yl)methanol; (1,1-Dimethylethyl)(1H-imidazol-2-yl)methanol
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole-2-Methanol,α-(1,1-Dimethylethyl)-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to traceability and documentation supports our clients' needs for regulatory compliance in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.