Description

(2E)-3-[2-[Acetyl(Phenyl)Amino]-1,3-Thiazol-4-Yl]Acrylic Acid is a high-purity, specialized organic intermediate featuring a thiazole-acrylic acid scaffold. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical agents, enabling the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas requiring thiazole and acrylic acid pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or emissive layer materials in electronic displays and lighting.
• Ligand Synthesis for Catalysis: Employed in the preparation of novel ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Bioconjugation & Probe Development: The acrylic acid moiety can be utilized for Michael addition or other conjugation chemistries in biochemical probe and linker synthesis.
• Polymer & Material Science: Acts as a functional monomer or cross-linker for creating specialty polymers with tailored thermal or optical properties.

Basic Information

Product Name	(2E)-3-[2-[Acetyl(Phenyl)Amino]-1,3-Thiazol-4-Yl]Acrylic Acid
CAS No.	756859-00-4
Molecular Formula	C14H12N2O3S
Molecular Weight	288.32 g/mol
Synonyms	(E)-3-(2-(Acetyl(phenyl)amino)thiazol-4-yl)acrylic acid; 2-Propenoic acid, 3-[2-[acetyl(phenyl)amino]-4-thiazolyl]-, (2E)-; 4-Thiazoleacrylic acid, 2-(N-acetyl-N-phenylamino)-, (E)-; N-Acetyl-N-phenyl-4-thiazolylacrylamide-2-carboxylic acid; (2E)-3-[2-(Acetylanilino)-1,3-thiazol-4-yl]prop-2-enoic acid; 756859-00-4; Acetylphenylaminothiazole acrylic acid
EINECS	Contact for details

Quality Control

Our (2E)-3-[2-[Acetyl(Phenyl)Amino]-1,3-Thiazol-4-Yl]Acrylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.